Opioids as Triggers of the Adaptive Phenomenon of Ischemic Preconditioning of the Heart

Opioids as Triggers of the Adaptive Phenomenon of Ischemic Preconditioning of the Heart

Détails bibliographiques
Parent link:Neuroscience and Behavioral Physiology.— , 1967-
Vol. 46, iss. 3.— 2016.— [P. 319-327]
Collectivité auteur: Национальный исследовательский Томский политехнический университет Институт природных ресурсов Кафедра экономики природных ресурсов
Autres auteurs: Maslov L. N. Leonid Nikolaevich, Naryzhnaya N. V. Nataliya Vladimirovna, Podoksenov Yu. K. Yury Kirilovich, Mrochek A. G. Aleksandr Gennadievich, Gorbunov A. S. Aleksandr Sergeevich, Tsibulnikov S. Yu. Sergey Yurjevich
Résumé:Title screen
Transient ischemia/reperfusion has been shown to evoke increases in enkephalin levels in myocardial tissue. Blockade of δ opioid receptors eliminates the cardioprotective effect of ischemic preconditioning both in vivo and in vitro. Inhibition of κ1 opioid receptors eliminates the cardioprotective effect of preconditioning only in vitro. Agonists of μ, δ1, δ2, and κ1 opioid receptors imitate the cardioprotective effect of preconditioning. These results indicate that endogenous opioid peptides are triggers of ischemic preconditioning.
Режим доступа: по договору с организацией-держателем ресурса
Publié: 2016
Sujets:
электронный ресурс
труды учёных ТПУ
Accès en ligne:http://dx.doi.org/10.1007/s11055-016-0236-7
Format: Électronique Chapitre de livre
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=647811

Internet

http://dx.doi.org/10.1007/s11055-016-0236-7

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