Opioids as Triggers of the Adaptive Phenomenon of Ischemic Preconditioning of the Heart

Opioids as Triggers of the Adaptive Phenomenon of Ischemic Preconditioning of the Heart

Bibliografski detalji
Parent link:Neuroscience and Behavioral Physiology.— , 1967-
Vol. 46, iss. 3.— 2016.— [P. 319-327]
Autor kompanije: Национальный исследовательский Томский политехнический университет Институт природных ресурсов Кафедра экономики природных ресурсов
Daljnji autori: Maslov L. N. Leonid Nikolaevich, Naryzhnaya N. V. Nataliya Vladimirovna, Podoksenov Yu. K. Yury Kirilovich, Mrochek A. G. Aleksandr Gennadievich, Gorbunov A. S. Aleksandr Sergeevich, Tsibulnikov S. Yu. Sergey Yurjevich
Sažetak:Title screen
Transient ischemia/reperfusion has been shown to evoke increases in enkephalin levels in myocardial tissue. Blockade of δ opioid receptors eliminates the cardioprotective effect of ischemic preconditioning both in vivo and in vitro. Inhibition of κ1 opioid receptors eliminates the cardioprotective effect of preconditioning only in vitro. Agonists of μ, δ1, δ2, and κ1 opioid receptors imitate the cardioprotective effect of preconditioning. These results indicate that endogenous opioid peptides are triggers of ischemic preconditioning.
Режим доступа: по договору с организацией-держателем ресурса
Jezik:engleski
Izdano: 2016
Teme:
электронный ресурс
труды учёных ТПУ
Online pristup:http://dx.doi.org/10.1007/s11055-016-0236-7
Format: Elektronički Poglavlje knjige
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=647811

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