Opioids as Triggers of the Adaptive Phenomenon of Ischemic Preconditioning of the Heart

Opioids as Triggers of the Adaptive Phenomenon of Ischemic Preconditioning of the Heart

Podrobná bibliografie
Parent link:Neuroscience and Behavioral Physiology.— , 1967-
Vol. 46, iss. 3.— 2016.— [P. 319-327]
Korporativní autor: Национальный исследовательский Томский политехнический университет Институт природных ресурсов Кафедра экономики природных ресурсов
Další autoři: Maslov L. N. Leonid Nikolaevich, Naryzhnaya N. V. Nataliya Vladimirovna, Podoksenov Yu. K. Yury Kirilovich, Mrochek A. G. Aleksandr Gennadievich, Gorbunov A. S. Aleksandr Sergeevich, Tsibulnikov S. Yu. Sergey Yurjevich
Shrnutí:Title screen
Transient ischemia/reperfusion has been shown to evoke increases in enkephalin levels in myocardial tissue. Blockade of δ opioid receptors eliminates the cardioprotective effect of ischemic preconditioning both in vivo and in vitro. Inhibition of κ1 opioid receptors eliminates the cardioprotective effect of preconditioning only in vitro. Agonists of μ, δ1, δ2, and κ1 opioid receptors imitate the cardioprotective effect of preconditioning. These results indicate that endogenous opioid peptides are triggers of ischemic preconditioning.
Режим доступа: по договору с организацией-держателем ресурса
Vydáno: 2016
Témata:
электронный ресурс
труды учёных ТПУ
On-line přístup:http://dx.doi.org/10.1007/s11055-016-0236-7
Médium: Elektronický zdroj Kapitola
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=647811

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