Opioids as Triggers of the Adaptive Phenomenon of Ischemic Preconditioning of the Heart; Neuroscience and Behavioral Physiology; Vol. 46, iss. 3
| Parent link: | Neuroscience and Behavioral Physiology.— , 1967- Vol. 46, iss. 3.— 2016.— [P. 319-327] |
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| Collectivité auteur: | |
| Autres auteurs: | , , , , , |
| Résumé: | Title screen Transient ischemia/reperfusion has been shown to evoke increases in enkephalin levels in myocardial tissue. Blockade of δ opioid receptors eliminates the cardioprotective effect of ischemic preconditioning both in vivo and in vitro. Inhibition of κ1 opioid receptors eliminates the cardioprotective effect of preconditioning only in vitro. Agonists of μ, δ1, δ2, and κ1 opioid receptors imitate the cardioprotective effect of preconditioning. These results indicate that endogenous opioid peptides are triggers of ischemic preconditioning. Режим доступа: по договору с организацией-держателем ресурса |
| Langue: | anglais |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | http://dx.doi.org/10.1007/s11055-016-0236-7 |
| Format: | Électronique Chapitre de livre |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=647811 |
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| 200 | 1 | |a Opioids as Triggers of the Adaptive Phenomenon of Ischemic Preconditioning of the Heart |f L. N. Maslov [et al.] | |
| 203 | |a Text |c electronic | ||
| 300 | |a Title screen | ||
| 320 | |a [References: p. 327 (80 tit.)] | ||
| 330 | |a Transient ischemia/reperfusion has been shown to evoke increases in enkephalin levels in myocardial tissue. Blockade of δ opioid receptors eliminates the cardioprotective effect of ischemic preconditioning both in vivo and in vitro. Inhibition of κ1 opioid receptors eliminates the cardioprotective effect of preconditioning only in vitro. Agonists of μ, δ1, δ2, and κ1 opioid receptors imitate the cardioprotective effect of preconditioning. These results indicate that endogenous opioid peptides are triggers of ischemic preconditioning. | ||
| 333 | |a Режим доступа: по договору с организацией-держателем ресурса | ||
| 461 | |t Neuroscience and Behavioral Physiology |d 1967- | ||
| 463 | |t Vol. 46, iss. 3 |v [P. 319-327] |d 2016 | ||
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a труды учёных ТПУ | |
| 701 | 1 | |a Maslov |b L. N. |g Leonid Nikolaevich | |
| 701 | 1 | |a Naryzhnaya |b N. V. |g Nataliya Vladimirovna | |
| 701 | 1 | |a Podoksenov |b Yu. K. |g Yury Kirilovich | |
| 701 | 1 | |a Mrochek |b A. G. |g Aleksandr Gennadievich | |
| 701 | 1 | |a Gorbunov |b A. S. |g Aleksandr Sergeevich | |
| 701 | 1 | |a Tsibulnikov |b S. Yu. |c specialist in the field of medical technology |c Senior Lecturer of Tomsk Polytechnic University, Candidate of medical Sciences |f 1986- |g Sergey Yurjevich |3 (RuTPU)RU\TPU\pers\36547 |9 19595 | |
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