Antioxidant and Immunotropic Properties of some Lithium Salts
| Parent link: | Journal of Applied Pharmaceutical Science Vol. 6 (1).— 2016.— [P. 86-89] |
|---|---|
| Yhteisötekijät: | , |
| Muut tekijät: | , , , , , , , , , |
| Yhteenveto: | Title screen Objective: The antioxidant activity and immuno-tropic effects of lithium glutamate, lithium salicylate, lithium benzoate and lithium lactate have been investigated in this work, as a base for new psychotropic medicines. Methods: The antioxidant properties were studied by the voltammetric method. Phagocytic activity of neutrophilic leucocytes and the reaction of blastic transformation of lymphocytes were used as test for assessments of influence of the lithium compounds on the immune cells of human blood. Results: It was revealed absence of toxic action on human blood cells for all tested substances. Lithium benzoate showed the most significant stimulating influence on lymphocytes. Glutamate and benzoate lithium expressed scavenging activity vs oxygen radicals. Salicylate and benzoate lithium revealed significant phagocytosis stimulation effects. Conclusion: Investigated lithium salts expressed antioxidant activity and immunotropic effects, all investigated substance are of interest in medical application for mental diseases and comorbid pathology treatment. |
| Kieli: | englanti |
| Julkaistu: |
2016
|
| Aiheet: | |
| Linkit: | http://dx.doi.org/10.7324/JAPS.2016.600115 |
| Aineistotyyppi: | Elektroninen Kirjan osa |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=646827 |
MARC
| LEADER | 00000naa0a2200000 4500 | ||
|---|---|---|---|
| 001 | 646827 | ||
| 005 | 20250203092544.0 | ||
| 035 | |a (RuTPU)RU\TPU\network\11964 | ||
| 090 | |a 646827 | ||
| 100 | |a 20160317d2016 k||y0rusy50 ba | ||
| 101 | 0 | |a eng | |
| 135 | |a drcn ---uucaa | ||
| 181 | 0 | |a i | |
| 182 | 0 | |a b | |
| 200 | 1 | |a Antioxidant and Immunotropic Properties of some Lithium Salts |f E. V. Plotnikov [et al.] | |
| 203 | |a Text |c electronic | ||
| 300 | |a Title screen | ||
| 320 | |a [References: p. 89 (16 tit.)] | ||
| 330 | |a Objective: The antioxidant activity and immuno-tropic effects of lithium glutamate, lithium salicylate, lithium benzoate and lithium lactate have been investigated in this work, as a base for new psychotropic medicines. Methods: The antioxidant properties were studied by the voltammetric method. Phagocytic activity of neutrophilic leucocytes and the reaction of blastic transformation of lymphocytes were used as test for assessments of influence of the lithium compounds on the immune cells of human blood. Results: It was revealed absence of toxic action on human blood cells for all tested substances. Lithium benzoate showed the most significant stimulating influence on lymphocytes. Glutamate and benzoate lithium expressed scavenging activity vs oxygen radicals. Salicylate and benzoate lithium revealed significant phagocytosis stimulation effects. Conclusion: Investigated lithium salts expressed antioxidant activity and immunotropic effects, all investigated substance are of interest in medical application for mental diseases and comorbid pathology treatment. | ||
| 461 | |t Journal of Applied Pharmaceutical Science | ||
| 463 | |t Vol. 6 (1) |v [P. 86-89] |d 2016 | ||
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a труды учёных ТПУ | |
| 610 | 1 | |a антиоксиданты | |
| 610 | 1 | |a иммунотропные эффекты | |
| 610 | 1 | |a вольтамперометрия | |
| 610 | 1 | |a фагоцитоз | |
| 610 | 1 | |a психические заболевания | |
| 610 | 1 | |a литий глутамата | |
| 610 | 1 | |a салицилат лития | |
| 610 | 1 | |a литий бензоат | |
| 610 | 1 | |a лактата лития | |
| 701 | 1 | |a Plotnikov |b E. V. |c chemist |c Associate Professor of Tomsk Polytechnic University, Candidate of Chemical Sciences |f 1983- |g Evgeny Vladimirovich |3 (RuTPU)RU\TPU\pers\32469 |9 16417 | |
| 701 | 1 | |a Voronova |b O. A. |c chemist |c Assistant of Tomsk Polytechnic University, Candidate of chemical sciences |f 1979- |g Olesya Aleksandrovna |3 (RuTPU)RU\TPU\pers\32169 |9 16170 | |
| 701 | 1 | |a Linert |b W. |g Wolfgang | |
| 701 | 1 | |a Martemyanov |b D. V. |c chemist |c Engineer-researcher of Tomsk Polytechnic University |f 1978- |g Dmitry Vladimirovich |3 (RuTPU)RU\TPU\pers\31283 |9 15461 | |
| 701 | 1 | |a Korotkova |b E. I. |c chemist |c Professor of Tomsk Polytechnic University, Doctor of chemical science |f 1965- |g Elena Ivanovna |3 (RuTPU)RU\TPU\pers\31278 |9 15456 | |
| 701 | 1 | |a Dorozhko |b E. V. |c chemist |c Engineer of Tomsk Polytechnic University |f 1979- |g Elena Vladimirovna |3 (RuTPU)RU\TPU\pers\32174 |9 16175 | |
| 701 | 1 | |a Astashkina |b A. P. |c chemist |c Associate Professor of Tomsk Polytechnic University, Candidate of chemical sciences |f 1984- |g Anna Pavlovna |3 (RuTPU)RU\TPU\pers\31266 |9 15444 | |
| 701 | 1 | |a Martemjyanova |b I. V. |g Irina Vladimirovna | |
| 701 | 1 | |a Ivanova |b S. A. |g Svetlana Aleksandrovna | |
| 701 | 1 | |a Bokhan |b N. A. |g Nikolay Aleksandrovich | |
| 712 | 0 | 2 | |a Национальный исследовательский Томский политехнический университет |b Институт природных ресурсов |b Кафедра физической и аналитической химии |3 (RuTPU)RU\TPU\col\18656 |9 27109 |
| 712 | 0 | 2 | |a Национальный исследовательский Томский политехнический университет |b Институт физики высоких технологий |b Лаборатория № 12 |3 (RuTPU)RU\TPU\col\19054 |9 27328 |
| 801 | 2 | |a RU |b 63413507 |c 20160317 |g RCR | |
| 856 | 4 | |u http://dx.doi.org/10.7324/JAPS.2016.600115 | |
| 942 | |c CF | ||