Study of Adsorption Doxorubicin by Iron-Carbon Composite Powders; Key Engineering Materials; Vol. 683 : Multifunctional Materials: Development and Application

Study of Adsorption Doxorubicin by Iron-Carbon Composite Powders; Key Engineering Materials; Vol. 683 : Multifunctional Materials: Development and Application

Bibliographic Details
Parent link:Key Engineering Materials: Scientific Journal
Vol. 683 : Multifunctional Materials: Development and Application.— 2016.— [P. 331-337]
Corporate Author: Национальный исследовательский Томский политехнический университет (ТПУ) Институт физики высоких технологий (ИФВТ) Кафедра общей химии и химической технологии (ОХХТ)
Other Authors: Yurmazova T. A. Tatyana Aleksandrovna, Ivanova V., Buldakov M., Galanov S.
Summary:Title screen
Method of electric-spark dispersion of iron particles in water, ethyl alcohol, phosphoric acid solution and hexane has been applied to produce composite magnetic nanosized powders. Their phase composition, dispersity, magnetic susceptibility, and adsorption-desorption properties towards anti-tumor remedy doxorubicin have been studied. It is shown that the obtained powder in hexane has the highest adsorption capacity towards doxorubicin. This is probably the evidence of surface compound formation. It is durable adsorption complex, which is formed from carbonyl and amine groups of organic cations and vacant orbitals of iron d-sublevel. The powder, obtained in hexane, can be dissolved in human blood plasma and amino acid solutions: possible time of iron elimination from human organism is smaller than 10 days. It is shown possibility of application iron-carbon sorbent is in quality of magnetic carrier doxorubicin to cancer cells.
Режим доступа: по договору с организацией-держателем ресурса
Language:English
Published: 2016
Series:Physicochemical Properties of Materials and Current Processing Technologies
Subjects:
электронный ресурс
труды учёных ТПУ
адсорбция
доксорубицин
наночастицы
железо-углерод
сорбенты
изотермы
композитные порошки
Online Access:http://dx.doi.org/10.4028/www.scientific.net/KEM.683.331
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=646627

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