Effect of Low-Dimensional Alumina Structures on Viability of L 929 Cells

Bibliographic Details
Parent link:AIP Conference Proceedings
Vol. 1683 : Advanced Materials with Hierarchical Structure for New Technologies and Reliable Structures.— 2015.— [020054, 4 p.]
Corporate Authors: Национальный исследовательский Томский политехнический университет (ТПУ) Институт физики высоких технологий (ИФВТ) Кафедра физики высоких технологий в машиностроении (ФВТМ), Национальный исследовательский Томский политехнический университет (ТПУ) Институт физики высоких технологий (ИФВТ) Кафедра физики высоких технологий в машиностроении (ФВТМ) Сетевая научно-образовательная лаборатория "Медицинское материаловедение" (СНОЛ ММ)
Other Authors: Fomenko A. N. Alla Nikolaevna, Korovin M. S. Matvey Sergeevich, Bakina O. V. Olga Vladimirovna, Kazantsev S. O. Sergey Olegovich, Glazkova E. A. Elena Alekseevna, Svarovskaya N. V. Natalia Valentinovna, Lozhkomoev A. S. Aleksandr Sergeevich
Summary:Title screen
In the study, we estimated the cytotoxicity of alumina nanoparticles differing in shape (nanofibers, nanoplates, nanosheets, agglomerates of nanosheets) and close in physicochemical properties (particle size, specific surface area, phase composition, and zeta potential). The alumina structures were characterized using transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray diffraction (XRD) data, low-temperature nitrogen adsorption, and dynamic light scattering (DLS). The cytotoxicity was estimated on fibroblast cells of the L929 line. It was found that a more adverse effect on the cells was exerted by alumina nanofibers and nanosheets. The action of nanosheets on the cells was inhibitory and was of about the same level, irrespective of the observation period. The effect of alumina nanosheet agglomerates and nanoplates on the cell proliferation was weak even at an exposure time of 72 h.
Режим доступа: по договору с организацией-держателем ресурса
Language:English
Published: 2015
Subjects:
Online Access:http://dx.doi.org/10.1063/1.4932744
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=644892

MARC

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200 1 |a Effect of Low-Dimensional Alumina Structures on Viability of L 929 Cells  |f A. N. Fomenko [et al.] 
203 |a Text  |c electronic 
300 |a Title screen 
320 |a [References: 18 tit.] 
330 |a In the study, we estimated the cytotoxicity of alumina nanoparticles differing in shape (nanofibers, nanoplates, nanosheets, agglomerates of nanosheets) and close in physicochemical properties (particle size, specific surface area, phase composition, and zeta potential). The alumina structures were characterized using transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray diffraction (XRD) data, low-temperature nitrogen adsorption, and dynamic light scattering (DLS). The cytotoxicity was estimated on fibroblast cells of the L929 line. It was found that a more adverse effect on the cells was exerted by alumina nanofibers and nanosheets. The action of nanosheets on the cells was inhibitory and was of about the same level, irrespective of the observation period. The effect of alumina nanosheet agglomerates and nanoplates on the cell proliferation was weak even at an exposure time of 72 h. 
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701 1 |a Korovin  |b M. S.  |c specialist in the field of medical technology  |c researcher of Tomsk Polytechnic University, candidate of biological sciences  |f 1980-  |g Matvey Sergeevich  |3 (RuTPU)RU\TPU\pers\35814 
701 1 |a Bakina  |b O. V.  |c specialist in the field of medical technology  |c researcher of Tomsk Polytechnic University  |f 1979-  |g Olga Vladimirovna  |3 (RuTPU)RU\TPU\pers\34696 
701 1 |a Kazantsev  |b S. O.  |c specialist in the field of material science  |c engineer of Tomsk Polytechnic University  |f 1991-  |g Sergey Olegovich  |3 (RuTPU)RU\TPU\pers\35794 
701 1 |a Glazkova  |b E. A.  |c specialist in the field of medical technology  |c senior researcher of Tomsk Polytechnic University  |f 1963-  |g Elena Alekseevna  |3 (RuTPU)RU\TPU\pers\34699 
701 1 |a Svarovskaya  |b N. V.  |c specialist in the field of medical technology  |c senior researcher of Tomsk Polytechnic University  |f 1965-  |g Natalia Valentinovna  |3 (RuTPU)RU\TPU\pers\34703 
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