Effect of Low-Dimensional Alumina Structures on Viability of L 929 Cells; AIP Conference Proceedings; Vol. 1683 : Advanced Materials with Hierarchical Structure for New Technologies and Reliable Structures

Dettagli Bibliografici
Parent link:AIP Conference Proceedings
Vol. 1683 : Advanced Materials with Hierarchical Structure for New Technologies and Reliable Structures.— 2015.— [020054, 4 p.]
Enti autori: Национальный исследовательский Томский политехнический университет (ТПУ) Институт физики высоких технологий (ИФВТ) Кафедра физики высоких технологий в машиностроении (ФВТМ), Национальный исследовательский Томский политехнический университет (ТПУ) Институт физики высоких технологий (ИФВТ) Кафедра физики высоких технологий в машиностроении (ФВТМ) Сетевая научно-образовательная лаборатория "Медицинское материаловедение" (СНОЛ ММ)
Altri autori: Fomenko A. N. Alla Nikolaevna, Korovin M. S. Matvey Sergeevich, Bakina O. V. Olga Vladimirovna, Kazantsev S. O. Sergey Olegovich, Glazkova E. A. Elena Alekseevna, Svarovskaya N. V. Natalia Valentinovna, Lozhkomoev A. S. Aleksandr Sergeevich
Riassunto:Title screen
In the study, we estimated the cytotoxicity of alumina nanoparticles differing in shape (nanofibers, nanoplates, nanosheets, agglomerates of nanosheets) and close in physicochemical properties (particle size, specific surface area, phase composition, and zeta potential). The alumina structures were characterized using transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray diffraction (XRD) data, low-temperature nitrogen adsorption, and dynamic light scattering (DLS). The cytotoxicity was estimated on fibroblast cells of the L929 line. It was found that a more adverse effect on the cells was exerted by alumina nanofibers and nanosheets. The action of nanosheets on the cells was inhibitory and was of about the same level, irrespective of the observation period. The effect of alumina nanosheet agglomerates and nanoplates on the cell proliferation was weak even at an exposure time of 72 h.
Режим доступа: по договору с организацией-держателем ресурса
Lingua:inglese
Pubblicazione: 2015
Soggetti:
Accesso online:http://dx.doi.org/10.1063/1.4932744
Natura: Elettronico Capitolo di libro
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=644892
Descrizione
Riassunto:Title screen
In the study, we estimated the cytotoxicity of alumina nanoparticles differing in shape (nanofibers, nanoplates, nanosheets, agglomerates of nanosheets) and close in physicochemical properties (particle size, specific surface area, phase composition, and zeta potential). The alumina structures were characterized using transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray diffraction (XRD) data, low-temperature nitrogen adsorption, and dynamic light scattering (DLS). The cytotoxicity was estimated on fibroblast cells of the L929 line. It was found that a more adverse effect on the cells was exerted by alumina nanofibers and nanosheets. The action of nanosheets on the cells was inhibitory and was of about the same level, irrespective of the observation period. The effect of alumina nanosheet agglomerates and nanoplates on the cell proliferation was weak even at an exposure time of 72 h.
Режим доступа: по договору с организацией-держателем ресурса
DOI:10.1063/1.4932744