Pharmacokinetic studies of new silver-based complex

Pharmacokinetic studies of new silver-based complex

Chi tiết về thư mục
Parent link:	International Journal of Pharmacy and Pharmaceutical Sciences: Scientific Journal.— , 2009- Vol. 7, iss. 6.— 2015.— [P. 41-43]
Tác giả chính:	Silnikov V. A. Vladimir
Tác giả của công ty:	Национальный исследовательский Томский политехнический университет (ТПУ) Институт природных ресурсов (ИПР) Кафедра физической и аналитической химии (ФАХ)
Tác giả khác:	Plotnikov E. V. Evgeny Vladimirovich, Plotnikov V. M. Vladimir Mikhaylovich
Tóm tắt:	Title screen Objective: Investigation of pharmacokinetics parameters of the new silver-based compound of general formula C6H19Ag2N4LiO6S2, called “Argosil”, with high antiviral activity. Methods: Water solution of complex administered intragastrically in the dose rate of 100 mg/kg body weight of mice BALB/c (males) aged 1.5-2.0 mo. Blood and tissues samples analyzed by mass spectrometry. Results: Half-life of the drug was about 4 h at the initial stage. About 5% of the initially introduced silver detected after 24 h. Maximum drug concentration observed in the lung tissues. Conclusion: Results make the basis for further test and clinical implementation. Taken into account low toxicity and antiviral properties of this compound, it looks especially effective for lung infections treatment.
Ngôn ngữ:	Tiếng Anh
Được phát hành:	2015
Những chủ đề:	труды учёных ТПУ электронный ресурс
Truy cập trực tuyến:	http://innovareacademics.in/journals/index.php/ijpps/article/view/5396
Định dạng:	Điện tử Chương của sách
KOHA link:	https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=643388

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