Study of physicochemical and biological properties of calcium phosphate coatings prepared by RF magnetron sputtering of silicon-substituted hydroxyapatite

Study of physicochemical and biological properties of calcium phosphate coatings prepared by RF magnetron sputtering of silicon-substituted hydroxyapatite

Detalhes bibliográficos
Parent link:Journal of Surface Investigation. X-ray, Synchrotron and Neutron Techniques: Scientific Journal
Vol. 5, iss. 5.— 2011.— [P. 863-869]
Outros Autores: Pichugin V. F. Vladimir Fyodorovich, Surmeneva M. A. Maria Alexandrovna, Surmenev R. A. Roman Anatolievich, Khlusov I. A. Igor Albertovich, Epple M.
Resumo:Title screen
Coatings based on pure silicon and silicon-substituted hydroxyapatite were grown by RF magnetron sputtering. The coating surface morphology, phase and elemental composition were studied by scanning electron microscopy, energy-dispersive X-ray analysis, and infrared spectroscopy. It was found that coatings are X-ray-amorphous, their elemental composition being controlled by the sputtered target composition. The distribution of elements over the coating surface is homogeneous. Medical and biological properties of coatings were studied in vivo and in vitro. Osteogenic properties of coatings were studied. Coatings grown by sputtering of a stoichiometric hydroxyapatite target are biocompatible without osteoinductive activity. The introduction of silicate ions into the hydroxyapatite structure that forms an electrode target significantly enhances the in vivo effect of CaP magnetron coatings on the osteogenic activity and stromal bone-marrow stem cells.
Режим доступа: по договору с организацией-держателем ресурса
Idioma:inglês
Publicado em: 2011
Assuntos:
электронный ресурс
труды учёных ТПУ
Acesso em linha:http://dx.doi.org/10.1134/S1027451011090138
Formato: Recurso Electrónico Capítulo de Livro
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=642692

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