Antibacterial AgNPs/CaP biocomposites; The 9th International Forum on on Strategic Techology (IFOST-2014), September 21-23, 2014, Cox's Bazar, Bangladesh

Bibliographic Details
Parent link:The 9th International Forum on on Strategic Techology (IFOST-2014), September 21-23, 2014, Cox's Bazar, Bangladesh.— 2014.— [P. 472-474]
Corporate Authors: Национальный исследовательский Томский политехнический университет (ТПУ) Физико-технический институт (ФТИ) Кафедра теоретической и экспериментальной физики (ТиЭФ), Национальный исследовательский Томский политехнический университет (ТПУ) Физико-технический институт (ФТИ) Кафедра теоретической и экспериментальной физики (ТиЭФ) Центр технологий (ЦТ)
Other Authors: Ivanova A. A. Anna Aleksandrovna, Surmenev R. A. Roman Anatolievich, Surmeneva M. A. Maria Alexandrovna, Mukhametkaliev T. M. Timur Mukhamedrashidovich, Sharonova A. A. Anna Aleksandrovna, Grubova I. Yu. Irina Yurievna, Loza K., Chernousova S., Prymak O., Epple M.
Summary:Title screen
The modification of implant surface is in the focus of many scientists worldwide. In this study, multifunctional biocomposite on the basis of calcium phosphate coating and silver nanoparticles has been fabricated through the use of nanofabrication techniques. Dense nanocrystalline HA film was deposited over AgNPs. The properties as well as the in vitro behavior of the developed biocomposites have been studied. The diffraction patterns of the biocomposites revealed the peaks of crystalline HA and silver (Ag). The release of Ag from the developed biocomposites was evaluated. The concentration of the released silver ions for 7 days of dissolution was 0.27±0.02 µg/mL and 0.54±0.02 µg/mL for phosphate and acetate buffers, respectively. In order to estimate the cytotoxicity of the samples the functional activity of osteoclasts, in particular, cell morphology, multinuclearity, actin ring and resorption pit on the substrates coated with HA and AgNPs-HA have been evaluated.
Режим доступа: по договору с организацией-держателем ресурса
Language:English
Published: 2014
Subjects:
Online Access:http://dx.doi.org/10.1109/IFOST.2014.6991166
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=641657

MARC

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330 |a The modification of implant surface is in the focus of many scientists worldwide. In this study, multifunctional biocomposite on the basis of calcium phosphate coating and silver nanoparticles has been fabricated through the use of nanofabrication techniques. Dense nanocrystalline HA film was deposited over AgNPs. The properties as well as the in vitro behavior of the developed biocomposites have been studied. The diffraction patterns of the biocomposites revealed the peaks of crystalline HA and silver (Ag). The release of Ag from the developed biocomposites was evaluated. The concentration of the released silver ions for 7 days of dissolution was 0.27±0.02 µg/mL and 0.54±0.02 µg/mL for phosphate and acetate buffers, respectively. In order to estimate the cytotoxicity of the samples the functional activity of osteoclasts, in particular, cell morphology, multinuclearity, actin ring and resorption pit on the substrates coated with HA and AgNPs-HA have been evaluated. 
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