Study of MWNTS Influence upon Liver Histological and Histochemical Parameters in Laboratory Mice: Preliminary Results; Advanced Materials Research; Vol. 1085 : Prospects of Fundamental Sciences Development (PFSD-2014)

Bibliographic Details
Parent link:Advanced Materials Research: Scientific Journal
Vol. 1085 : Prospects of Fundamental Sciences Development (PFSD-2014).— 2015.— [P. 376-383]
Corporate Author: Томский политехнический университет
Other Authors: Vasyukova I. A., Gusev A. A., Ubogov A. Y., Godymchuk (Godimchuk) A. Yu. Anna Yuryevna
Summary:Title screen
Preliminary evaluation of toxic effect of commercially manufactured carbon nanostructured material based on multi-walled carbon nanotubes (MWCNT) upon laboratory mice C57B6/DBA2 males was carried out. It was found that thirty-day oral administration of nanotubes in doses of 0.3 and 3 mg/kg has no effect on liver condition, while administration of 30 mg/kg leads to formation of inflammatory infiltrates together with hepatocyte structure modification. The obtained results are of potential interest for development of industrial safety standards in nanomaterial handling and for development of standards for reproductive toxicity of carbon nanomaterials.
Режим доступа: по договору с организацией-держателем ресурса
Language:English
Published: 2015
Series:Material Science in Biology and Medicine
Subjects:
Online Access:http://dx.doi.org/10.4028/www.scientific.net/AMR.1085.376
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=641248

MARC

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330 |a Preliminary evaluation of toxic effect of commercially manufactured carbon nanostructured material based on multi-walled carbon nanotubes (MWCNT) upon laboratory mice C57B6/DBA2 males was carried out. It was found that thirty-day oral administration of nanotubes in doses of 0.3 and 3 mg/kg has no effect on liver condition, while administration of 30 mg/kg leads to formation of inflammatory infiltrates together with hepatocyte structure modification. The obtained results are of potential interest for development of industrial safety standards in nanomaterial handling and for development of standards for reproductive toxicity of carbon nanomaterials. 
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