Stability of Gold Nanoparticles Functionalized with Aminoacids
| Parent link: | Advanced Materials Research : Advanced materials, synthesis, development and application: Scientific Journal Vol. 880 : Prospects of Fundamental Sciences Development (PFSD-2013).— 2014.— [P. 253-258] |
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| Corporate Author: | |
| Other Authors: | , , , , |
| Summary: | Title screen While bio(organic-inorganic) compatibility and absence of cytotoxicity are crucial to create a successful nanocarrier for applications in biosensing and drug delivery, the study of its stability before commercialization is quite important. In the present work, the stability of gold nanoparticles (AuNPs) functionalized with L-Cysteine (Cys) and Cysteine-Glycine (Cys-Gly) was studied. The AuNPs surface modification with Cys and CysGly was performed to improve their biocompatibility and, after that, the stability of capped AuNPs was investigated. The synthetized AuNPs using 10 mM of cysteine and 20 mM of Cys demonstrated stability after 1 month of storage, while all other concentration ratios resulted in the formation of chain-like conglomerates. For AuNP capped with CysGly all modifier concentrations led to stable samples within 1 month of storage. Режим доступа: по договору с организацией-держателем ресурса |
| Published: |
2014
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| Series: | Chemistry and Physics of Materials Surface |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.4028/www.scientific.net/AMR.880.253 |
| Format: | Electronic Book Chapter |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=640721 |
| Summary: | Title screen While bio(organic-inorganic) compatibility and absence of cytotoxicity are crucial to create a successful nanocarrier for applications in biosensing and drug delivery, the study of its stability before commercialization is quite important. In the present work, the stability of gold nanoparticles (AuNPs) functionalized with L-Cysteine (Cys) and Cysteine-Glycine (Cys-Gly) was studied. The AuNPs surface modification with Cys and CysGly was performed to improve their biocompatibility and, after that, the stability of capped AuNPs was investigated. The synthetized AuNPs using 10 mM of cysteine and 20 mM of Cys demonstrated stability after 1 month of storage, while all other concentration ratios resulted in the formation of chain-like conglomerates. For AuNP capped with CysGly all modifier concentrations led to stable samples within 1 month of storage. Режим доступа: по договору с организацией-держателем ресурса |
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| DOI: | 10.4028/www.scientific.net/AMR.880.253 |