Preparation Technique of Technetium-99m-Labeled Nanoparticles of Fe@C with Modified Surface

Preparation Technique of Technetium-99m-Labeled Nanoparticles of Fe@C with Modified Surface

Bibliographic Details
Parent link:Advanced Materials Research : Radiation and nuclear techniques in material science: Scientific Journal
Vol. 1084 : Physical-Technical Problems of Nuclear Science, Energy Generation, and Power Industry (PTPAI -2014).— 2015.— [P. 582-586]
Corporate Author: Национальный исследовательский Томский политехнический университет (ТПУ) Физико-технический институт (ФТИ) Лаборатория № 31 ядерного реактора (Лаборатория № 31 ЯК)
Other Authors: Skuridin V. S. Viktor Sergeyevich, Stasyuk (Stasiuk) E. S. Elena Sergeyevna, Rogov A. S. Alexander Sergeyevich, Varlamova N. V. Natalya Valeryevna, Nesterov E. A. Evgeny Alexandrovich, Sadkin V. L. Vladimir Leonidovich, Postnikov P. S. Pavel Sergeevich
Summary:Title screen
The authors have researched the possibility of radioactive {99m}Tc labeling of the surface of carbon-coated nano-sized ferrum Fe@C particles as well as Fe@C (IDA) particles modified by aryldiazonium tosilates. Non-modified particles proved to absorb up to 11.2 % of {99m}Тс injected amount. The value of atomic absorption does not exceed 0.736∙10{-9} g-at {99m}Тс per 1 g of Fe@C. No physical absorption is observed on modified particles of Fe@C (IDA). In chemical interaction of the particles with {99m}Tc in the presence of a reducing agent, Sn (II), the yield of the labeled product increases 1.5 times and reaches 21.3% of the total induced radioactivity of the radionuclide.
Режим доступа: по договору с организацией-держателем ресурса
Published: 2015
Series:Radiation Technologies in Medicine
Subjects:
электронный ресурс
труды учёных ТПУ
наноколлоиды
наночастицы
технеций-99м
Online Access:http://dx.doi.org/10.4028/www.scientific.net/AMR.1084.582
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=640471
Description
Summary:Title screen
The authors have researched the possibility of radioactive {99m}Tc labeling of the surface of carbon-coated nano-sized ferrum Fe@C particles as well as Fe@C (IDA) particles modified by aryldiazonium tosilates. Non-modified particles proved to absorb up to 11.2 % of {99m}Тс injected amount. The value of atomic absorption does not exceed 0.736∙10{-9} g-at {99m}Тс per 1 g of Fe@C. No physical absorption is observed on modified particles of Fe@C (IDA). In chemical interaction of the particles with {99m}Tc in the presence of a reducing agent, Sn (II), the yield of the labeled product increases 1.5 times and reaches 21.3% of the total induced radioactivity of the radionuclide.
Режим доступа: по договору с организацией-держателем ресурса
DOI:10.4028/www.scientific.net/AMR.1084.582

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