Experimental Investigation of {99m}Тс-Nanotech Used for Lymph Nodes Visualization

Bibliographic Details
Parent link:Advanced Materials Research : Radiation and nuclear techniques in material science: Scientific Journal
Vol. 1084 : Physical-Technical Problems of Nuclear Science, Energy Generation, and Power Industry (PTPAI -2014).— 2015.— [P. 389-392]
Corporate Authors: Национальный исследовательский Томский политехнический университет (ТПУ) Физико-технический институт (ФТИ) Лаборатория № 31 ядерного реактора (Лаборатория № 31 ЯР), Национальный исследовательский Томский политехнический университет (ТПУ) Физико-технический институт (ФТИ) Кафедра иностранных языков физико-технического института (ИЯФТ)
Other Authors: Sinilkin I. G. Ivan Gennadjevich, Chernov V. I. Vladimir Ivanovich, Titskaya А. А. Anna Aleksndrovna, Zelchan R. V. Roman Vladimirovich, Daneykina (Daneikina) N. V. Natalia Viktorovna
Summary:Title screen
Measurement of colloidal particles size was performed on a NICOMP 380 ZLS. Pharmacokinetics. Radiometry of the organs was carried out on γ-spectrometer. Measurement of the sizes of radioactive particles of {99m}Tc-nanotech showed that average dynamic diameter of RFP particle ranged from 16.7 to 24.5 nm. {99m}Tc-nanotech received by the blood is actively trapped by liver and spleen. Inguinal lymph node in all animals was clearly visualized during lymphoscintigraphy on the 15{th} minute. Maximum accumulation of {99m}Tc-nanotech was observed in 3 hours. Experimental study of radiopharmaceutical {99m}Tc-nanotech showed that the nanocolloid can be used for lymphoscintigraphy and visualization of “sentinel” nodes.
Режим доступа: по договору с организацией-держателем ресурса
Language:English
Published: 2015
Series:Radiation Technologies in Medicine
Subjects:
Online Access:http://dx.doi.org/10.4028/www.scientific.net/AMR.1084.389
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=640379
Description
Summary:Title screen
Measurement of colloidal particles size was performed on a NICOMP 380 ZLS. Pharmacokinetics. Radiometry of the organs was carried out on γ-spectrometer. Measurement of the sizes of radioactive particles of {99m}Tc-nanotech showed that average dynamic diameter of RFP particle ranged from 16.7 to 24.5 nm. {99m}Tc-nanotech received by the blood is actively trapped by liver and spleen. Inguinal lymph node in all animals was clearly visualized during lymphoscintigraphy on the 15{th} minute. Maximum accumulation of {99m}Tc-nanotech was observed in 3 hours. Experimental study of radiopharmaceutical {99m}Tc-nanotech showed that the nanocolloid can be used for lymphoscintigraphy and visualization of “sentinel” nodes.
Режим доступа: по договору с организацией-держателем ресурса
DOI:10.4028/www.scientific.net/AMR.1084.389