Facile Synthesis of Flexible Bis(pyrazol-1-yl)alkane and Related Ligands in a Superbasic Medium; European Journal of Organic Chemistry; Vol. 2007, iss. 30

Facile Synthesis of Flexible Bis(pyrazol-1-yl)alkane and Related Ligands in a Superbasic Medium; European Journal of Organic Chemistry; Vol. 2007, iss. 30

Bibliographic Details
Parent link:European Journal of Organic Chemistry: Scientific Journal
Vol. 2007, iss. 30.— 2007.— [P. 5112–5116]
Other Authors: Potapov A. S. Andrey Sergeevich, Domina G. A., Khlebnikov A. I. Andrey Ivanovich, Ogorodnikov V. D.
Summary:Title screen
Flexible ligands 1,3-bis(pyrazol-1-yl)propanes, bis[2-(pyrazol-1-yl)ethyl] ethers, and bis[2-(3,5-dimethylpyrazol-1-yl)ethyl]amine were prepared by a facile procedure involving the reaction of pyrazoles with 1,3-dibromopropane, bis(2-chloroethyl) ether or bis(2-chloroethyl)amine hydrochloride in a superbasic medium (dimethyl sulfoxide/potassium hydroxide). Reaction of bis(2-chloroethyl)amine and pyrazole unexpectedly led to 1,4-bis[2-(pyrazol-1-yl)ethyl]piperazine. The corresponding 4,4?-diiodo-substituted bis(pyrazole) derivatives were prepared by oxidative iodination with I2/HIO3/H2SO4 in acetic acid. Vilsmeier–Haak formylation of some of the prepared compounds yielded the corresponding dialdehydes.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
Language:English
Published: 2007
Subjects:
электронный ресурс
труды учёных ТПУ
Pyrazole derivatives
Superbasic systems
Chelating ligands
Iodination
Flexible ligands
Online Access:http://dx.doi.org/10.1002/ejoc.200700353
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=639608

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