Glutamate Concentration in the Serum of Patients with Schizophrenia; Procedia Chemistry; Vol. 10 : Chemistry and Chemical Engineering in XXI century

Glutamate Concentration in the Serum of Patients with Schizophrenia; Procedia Chemistry; Vol. 10 : Chemistry and Chemical Engineering in XXI century

Dades bibliogràfiques
Parent link:	Procedia Chemistry Vol. 10 : Chemistry and Chemical Engineering in XXI century.— 2014.— [P. 80-85]
Autor corporatiu:	Национальный исследовательский Томский политехнический университет (ТПУ) Институт неразрушающего контроля (ИНК) Кафедра экологии и безопасности жизнедеятельности (ЭБЖ)
Altres autors:	Ivanova S. A. Svetlana Aleksandrovna, Boyko A. S., Fedorenko O. Yu. Olga Yurievna, Krotenko N. M., Semke A. V., Bokhan N. A.
Sumari:	Title screen Glutamate is the major neurotransmitter with multiple functions in the central nervous system. Glutamate-mediated excitotoxicity is involved in the pathophysiological processes in schizophrenia. The purpose of this study was to determine the concentration of glutamate in the serum of patients with paranoid schizophrenia compared with healthy individuals, and depending on the duration of the schizophrenic process and leading clinical symptoms. We investigated the level of glutamate in the serum of 158 patients with paranoid schizophrenia and 94 healthy persons. Higher concentrations of glutamate in schizophrenic patients compared with healthy persons have been found. The maximum concentrations of glutamate were detected in patients with disease duration of more than ten years. Glutamate level in the serum does not depend on the prevailing negative or positive clinical symptoms. The increased concentration of glutamate can hypothetically contribute to dopaminergic and glutamatergic imbalance, leading to the development of psychotic symptoms and cognitive dysfunction. Режим доступа: по договору с организацией-держателем ресурса
Idioma:	anglès
Publicat:	2014
Matèries:	электронный ресурс труды учёных ТПУ сыворотка крови больные шизофрения глутамат нервная система концентрация эксайтотоксичность glutamate concentration schizophrenia excitotoxicity
Accés en línia:	http://dx.doi.org/10.1016/j.proche.2014.10.015 http://earchive.tpu.ru/handle/11683/35475
Format:	MixedMaterials Electrònic Capítol de llibre
KOHA link:	https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=639458

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