Study of DNA Interaction with Cobalt Ferrite Nanoparticles

Podrobná bibliografie
Parent link:Journal of Nanoscience and Nanotechnology.— , 2001-
Vol. 11, № 3.— 2011.— [P. 2673-2677]
Hlavní autor: Pershina A. G. Aleksandra Gennadievna
Další autoři: Sazonov A. E., Novikov D. V., Knyazev A. S., Izaak T. I., Itin V. I., Naiden E. P., Magaeva A. A., Terechova O. G.
Shrnutí:Title screen
Interaction of cobalt ferrite nanopowder and nucleic acid was investigated. Superparamagnetic cobalt ferrite nanoparticles (6–12 nm) were prepared by mechanochemical synthesis. Structure of the nanopowder was characterized using X-ray diffraction. It was shown that cobalt ferrite nanoparticles were associated with ssDNA and dsDNA in Tris-buffer resulting in bionanocomposite formation with mass weight relation nanoparticles: DNA 1:(0.083±0.003) and 1:(0.075±0.003) respectively. The mechanism of interaction between a DNA and cobalt ferrite nanoparticles was considered basing on the whole set of obtained data: FTIR-spectroscopy, analyzing desorption of DNA from the surface of the particles while changing the chemical content of the medium, and on the modeling interaction of specific biomolecule fragments with surface of a inorganic material. It was supposed that the linkage was based on coordination interaction of the phosphate groups and oxygen atoms heterocyclic bases of DNA with metal ions on the particle surface. These data can be used to design specific magnetic DNA-nanoparticles hybrid structures
Режим доступа: по договору с организацией-держателем ресурса
Vydáno: 2011
Témata:
On-line přístup:http://dx.doi.org/10.1166/jnn.2011.2739
Médium: Elektronický zdroj Kapitola
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=637293

MARC

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330 |a Interaction of cobalt ferrite nanopowder and nucleic acid was investigated. Superparamagnetic cobalt ferrite nanoparticles (6–12 nm) were prepared by mechanochemical synthesis. Structure of the nanopowder was characterized using X-ray diffraction. It was shown that cobalt ferrite nanoparticles were associated with ssDNA and dsDNA in Tris-buffer resulting in bionanocomposite formation with mass weight relation nanoparticles: DNA 1:(0.083±0.003) and 1:(0.075±0.003) respectively. The mechanism of interaction between a DNA and cobalt ferrite nanoparticles was considered basing on the whole set of obtained data: FTIR-spectroscopy, analyzing desorption of DNA from the surface of the particles while changing the chemical content of the medium, and on the modeling interaction of specific biomolecule fragments with surface of a inorganic material. It was supposed that the linkage was based on coordination interaction of the phosphate groups and oxygen atoms heterocyclic bases of DNA with metal ions on the particle surface. These data can be used to design specific magnetic DNA-nanoparticles hybrid structures 
333 |a Режим доступа: по договору с организацией-держателем ресурса 
461 |t Journal of Nanoscience and Nanotechnology  |d 2001- 
463 |t Vol. 11, № 3  |v [P. 2673-2677]  |d 2011 
610 1 |a электронный ресурс 
610 1 |a труды учёных ТПУ 
610 1 |a cobalt ferrite nanoparticles 
610 1 |a interaction 
610 1 |a nanobiocomposite 
610 1 |a nucleic acid 
700 1 |a Pershina  |b A. G.  |c biologist  |c Associate Professor of Tomsk Polytechnic University, Candidate of biological sciences  |f 1981-  |g Aleksandra Gennadievna  |3 (RuTPU)RU\TPU\pers\32466  |9 16414 
701 1 |a Sazonov  |b A. E. 
701 1 |a Novikov  |b D. V. 
701 1 |a Knyazev  |b A. S. 
701 1 |a Izaak  |b T. I. 
701 1 |a Itin  |b V. I. 
701 1 |a Naiden  |b E. P. 
701 1 |a Magaeva  |b A. A. 
701 1 |a Terechova  |b O. G. 
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