Применение [beta]-циклодекстрина для грануляции во взвешенном слое
| Parent link: | Перспективы развития фундаментальных наук=Prospects of Fundamental Sciences Development: сборник научных трудов XVII Международной конференции студентов, аспирантов и молодых ученых, г. Томск, 21-24 апреля 2020 г./ Национальный исследовательский Томский политехнический университет (ТПУ) ; под ред. И. А. Курзиной, Г. А. Вороновой.— , 2020 Т. 2 : Химия.— 2020.— [С. 41-43] |
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| Altres autors: | , |
| Sumari: | Заглавие с экрана In the present study, we investigated cyclodextrine as an excipient for tablet. In the pharmaceutical industry, the particulate ingredients are often granulated to improve their flowability and uniformity. A fluidized bed gas-solid drying is usually followed to remove the moisture that is introduced during the granulation. Fluidized bed granulation is a widely applied wet granulation technique in the pharmaceutical industry, exhibiting some technological advantages compared to the multistage wet granulation methods. Of the three available cyclodextrin forms, b-cyclodextrin is the most commonly used cyclodextrin in pharmaceutical formulations and the best studied cyclodextrin in humans. The possibility of using b-cyclodextrin in the production process of solid dosage forms using the technology of drying in a fluidized bed was confirmed. |
| Idioma: | rus |
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2020
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| Accés en línia: | http://earchive.tpu.ru/handle/11683/63009 |
| Format: | Electrònic Capítol de llibre |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=631549 |
| Sumari: | Заглавие с экрана In the present study, we investigated cyclodextrine as an excipient for tablet. In the pharmaceutical industry, the particulate ingredients are often granulated to improve their flowability and uniformity. A fluidized bed gas-solid drying is usually followed to remove the moisture that is introduced during the granulation. Fluidized bed granulation is a widely applied wet granulation technique in the pharmaceutical industry, exhibiting some technological advantages compared to the multistage wet granulation methods. Of the three available cyclodextrin forms, b-cyclodextrin is the most commonly used cyclodextrin in pharmaceutical formulations and the best studied cyclodextrin in humans. The possibility of using b-cyclodextrin in the production process of solid dosage forms using the technology of drying in a fluidized bed was confirmed. |
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