Гормоны стресса: кортизол, адренокортикотропный гормон и окситоцин в контексте социальных нарушений детей с расстройствами аутистического спектра; Перспективы развития фундаментальных наук; Т. 4 : Биология и фундаментальная медицина
| Parent link: | Перспективы развития фундаментальных наук=Prospects of Fundamental Sciences Development: сборник научных трудов XV Международной конференции студентов, аспирантов и молодых ученых, г. Томск, 24-27 апреля 2018 г./ Национальный исследовательский Томский политехнический университет (ТПУ) ; под ред. И. А. Курзиной, Г. А. Вороновой.— , 2018 Т. 4 : Биология и фундаментальная медицина.— 2018.— [С. 146-148] |
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| Summary: | Заглавие с экрана Autism spectrum disorders (ASD) refer to heterogeneous disorders of neurodevelopment, the main symptom of which is social insufficiency. Aim: to conduct a one-stage assessment of the relationship between key hormones in the regulation of social and stress responses: adrenocorticotropic hormone (ACTH), cortisol, oxytocin, in children with ASD in the context of severe social insufficiency. Materials and methods. A total of 44 children (37 boys and 7 girls) aged 3 to 12 years with a diagnosis of ASD were examined, which were divided into groups: with preserved social contact / lack of it. The concentrations of hormones were evaluated in blood plasma by the method of ELISA. Results. ACTH and cortisol demonstrate interdependent relationships without the involvement of oxytocin in children with ASD, while maintaining their social contact. In children with ASD with symptoms of social insufficiency, there are no correlations between the studied neurohormones. The conclusion. The data obtained suggest that the processes of disorganization / destruction of neuroanatomical and physiological connections between the systems of oxytocin and the hypothalamic-pituitary-adrenal axis (HPA-axis) and (or) the hypothalamic-neurohypophysis system and the HPA-axis. |
| Sprog: | russisk |
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2018
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| Online adgang: | http://earchive.tpu.ru/handle/11683/50915 |
| Format: | MixedMaterials Electronisk Book Chapter |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=627678 |
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| 200 | 1 | |a Гормоны стресса: кортизол, адренокортикотропный гормон и окситоцин в контексте социальных нарушений детей с расстройствами аутистического спектра |d Stress hormones: cortisol, adrenocorticotropic hormone and oxytocin in the context of social violations in children with autism spectrum disorders |f А. В. Тимофеева, Ю. Ю. Филиппова |g науч. рук. А. Л. Бурмистрова | |
| 203 | |a Текст |c электронный | ||
| 230 | |a 1 компьютерный файл (pdf; 176 Kb) | ||
| 300 | |a Заглавие с экрана | ||
| 320 | |a [Библиогр.: с. 148 (5 назв.)] | ||
| 330 | |a Autism spectrum disorders (ASD) refer to heterogeneous disorders of neurodevelopment, the main symptom of which is social insufficiency. Aim: to conduct a one-stage assessment of the relationship between key hormones in the regulation of social and stress responses: adrenocorticotropic hormone (ACTH), cortisol, oxytocin, in children with ASD in the context of severe social insufficiency. Materials and methods. A total of 44 children (37 boys and 7 girls) aged 3 to 12 years with a diagnosis of ASD were examined, which were divided into groups: with preserved social contact / lack of it. The concentrations of hormones were evaluated in blood plasma by the method of ELISA. Results. ACTH and cortisol demonstrate interdependent relationships without the involvement of oxytocin in children with ASD, while maintaining their social contact. In children with ASD with symptoms of social insufficiency, there are no correlations between the studied neurohormones. The conclusion. The data obtained suggest that the processes of disorganization / destruction of neuroanatomical and physiological connections between the systems of oxytocin and the hypothalamic-pituitary-adrenal axis (HPA-axis) and (or) the hypothalamic-neurohypophysis system and the HPA-axis. | ||
| 461 | 1 | |0 (RuTPU)RU\TPU\conf\26928 |t Перспективы развития фундаментальных наук |l Prospects of Fundamental Sciences Development |o сборник научных трудов XV Международной конференции студентов, аспирантов и молодых ученых, г. Томск, 24-27 апреля 2018 г. |o в 7 т. |f Национальный исследовательский Томский политехнический университет (ТПУ) ; под ред. И. А. Курзиной, Г. А. Вороновой |d 2018 | |
| 463 | 1 | |0 (RuTPU)RU\TPU\conf\26932 |t Т. 4 : Биология и фундаментальная медицина |v [С. 146-148] |d 2018 | |
| 510 | 1 | |a Stress hormones: cortisol, adrenocorticotropic hormone and oxytocin in the context of social violations in children with autism spectrum disorders |z eng | |
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a гормоны | |
| 610 | 1 | |a стрессы | |
| 610 | 1 | |a нарушения | |
| 610 | 1 | |a аутизм | |
| 610 | 1 | |a дети | |
| 700 | 1 | |a Тимофеева |b А. В. | |
| 701 | 1 | |a Филиппова |b Ю. Ю. | |
| 702 | 1 | |a Бурмистрова |b А. Л. |4 727 | |
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| 856 | 4 | |u http://earchive.tpu.ru/handle/11683/50915 | |
| 942 | |c BK | ||