Репертуар костномозговых клеток предшественников, ассоциированных с лимфогенным метастазированем у больных инвазивной карциномой неспецифического типа молочной железы; Перспективы развития фундаментальных наук; Т. 4 : Биология и фундаментальная медицина
| Parent link: | Перспективы развития фундаментальных наук=Prospects of Fundamental Sciences Development: сборник научных трудов XV Международной конференции студентов, аспирантов и молодых ученых, г. Томск, 24-27 апреля 2018 г./ Национальный исследовательский Томский политехнический университет (ТПУ) ; под ред. И. А. Курзиной, Г. А. Вороновой.— , 2018 Т. 4 : Биология и фундаментальная медицина.— 2018.— [С. 21-23] |
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| المؤلف الرئيسي: | |
| مؤلف مشترك: | |
| مؤلفون آخرون: | , , |
| الملخص: | Заглавие с экрана The high mortality of patients with breast cancer is determined by metastatic disease. It is thought that the metastatic disease development associated with the repertory of bone marrow progenitor cells in breast cancer patients. In our study the correlation between the bone marrow progenitor cells presences in the tumor and blood of patients and the lymphogenic metastasis development was studied. The main clinical and pathological parameters of 24 patients with invasive breast carcinoma of non-specific type were analyzed. Endothelial progenitor cells, mesenchymal stem cells, macrophage precursors, hematopoietic progenitor cells were detected with specific antibodies against CD34, CD133, CD90, VEGFR1, CD11b, CD45, CD202 in the cell-rich fluid from frozen tumor. The amount of MCP-1 in the patients blood serum was assessed by enzymelinked immunosorbent assay (ELISA), at a wavelength of 450 nm. The cytokines concentration was calculated from the calibration plot. The program package Statistica 10.0. was used for statistical data processing. The high risk of lymphogenic metastasis in patients who didn't complete a neoadjuvant chemotherapy course was associated with the number of HPC, EPC and MSC in tumor and MCP-1 in blood. |
| اللغة: | الروسية |
| منشور في: |
2018
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| الموضوعات: | |
| الوصول للمادة أونلاين: | http://earchive.tpu.ru/handle/11683/50868 |
| التنسيق: | الكتروني فصل الكتاب |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=627636 |
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| 200 | 1 | |a Репертуар костномозговых клеток предшественников, ассоциированных с лимфогенным метастазированем у больных инвазивной карциномой неспецифического типа молочной железы |d The repertory of bone marrow progenitor cells associated with lymphogenic metastasis in patients with invasive carcinoma of no special type |f А. В. Бузенкова, Р. Х. Мухамеджанов, Л. А. Таширева |g науч. рук. О. Е. Савельева | |
| 203 | |a Текст |c электронный | ||
| 230 | |a 1 компьютерный файл (pdf; 178 Kb) | ||
| 300 | |a Заглавие с экрана | ||
| 320 | |a [Библиогр.: с. 23 (3 назв.)] | ||
| 330 | |a The high mortality of patients with breast cancer is determined by metastatic disease. It is thought that the metastatic disease development associated with the repertory of bone marrow progenitor cells in breast cancer patients. In our study the correlation between the bone marrow progenitor cells presences in the tumor and blood of patients and the lymphogenic metastasis development was studied. The main clinical and pathological parameters of 24 patients with invasive breast carcinoma of non-specific type were analyzed. Endothelial progenitor cells, mesenchymal stem cells, macrophage precursors, hematopoietic progenitor cells were detected with specific antibodies against CD34, CD133, CD90, VEGFR1, CD11b, CD45, CD202 in the cell-rich fluid from frozen tumor. The amount of MCP-1 in the patients blood serum was assessed by enzymelinked immunosorbent assay (ELISA), at a wavelength of 450 nm. The cytokines concentration was calculated from the calibration plot. The program package Statistica 10.0. was used for statistical data processing. The high risk of lymphogenic metastasis in patients who didn't complete a neoadjuvant chemotherapy course was associated with the number of HPC, EPC and MSC in tumor and MCP-1 in blood. | ||
| 461 | 1 | |0 (RuTPU)RU\TPU\conf\26928 |t Перспективы развития фундаментальных наук |l Prospects of Fundamental Sciences Development |o сборник научных трудов XV Международной конференции студентов, аспирантов и молодых ученых, г. Томск, 24-27 апреля 2018 г. |o в 7 т. |f Национальный исследовательский Томский политехнический университет (ТПУ) ; под ред. И. А. Курзиной, Г. А. Вороновой |d 2018 | |
| 463 | 1 | |0 (RuTPU)RU\TPU\conf\26932 |t Т. 4 : Биология и фундаментальная медицина |v [С. 21-23] |d 2018 | |
| 510 | 1 | |a The repertory of bone marrow progenitor cells associated with lymphogenic metastasis in patients with invasive carcinoma of no special type |z eng | |
| 610 | 1 | |a электронный ресурс | |
| 610 | 1 | |a клетки | |
| 610 | 1 | |a молочные железы | |
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| 610 | 1 | |a костный мозг | |
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| 701 | 1 | |a Мухамеджанов |b Р. Х. | |
| 701 | 1 | |a Таширева |b Л. А. | |
| 702 | 1 | |a Савельева |b О. Е. |4 727 | |
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