Создание химерных а нтигенных рецепторов на основе 10-го домена фибронектина III типа; Перспективы развития фундаментальных наук; Т. 4 : Биология и фундаментальная медицина
| Parent link: | Перспективы развития фундаментальных наук=Prospects of Fundamental Sciences Development: сборник научных трудов XIV Международной конференции студентов, аспирантов и молодых ученых, г. Томск, 25-28 апреля 2017 г./ Национальный исследовательский Томский политехнический университет (ТПУ) ; под ред. И. А. Курзиной, Г. А. Вороновой.— , 2017 Т. 4 : Биология и фундаментальная медицина.— 2017.— [С. 154-156] |
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| Achoimre: | Заглавие с экрана Most of the CARs employ single-chain fragment of antibodies (scFv) as a target recognition module. ScFv, however, has some weak points, namely two-domain format and almost 30kDa weight. Here we describe CAR with the 10th human fibronectin type III domain as alternative antigen recognition module of CAR. We designed and developed mono- and bispecific Fn3CARs as a recognition module and proved their functionality. |
| Teanga: | Rúisis |
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2017
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| Rochtain ar líne: | http://earchive.tpu.ru/handle/11683/44884 |
| Formáid: | Leictreonach Caibidil leabhair |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=625091 |
| Achoimre: | Заглавие с экрана Most of the CARs employ single-chain fragment of antibodies (scFv) as a target recognition module. ScFv, however, has some weak points, namely two-domain format and almost 30kDa weight. Here we describe CAR with the 10th human fibronectin type III domain as alternative antigen recognition module of CAR. We designed and developed mono- and bispecific Fn3CARs as a recognition module and proved their functionality. |
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