Связь хитиназо -подобных белков с метастазированием у больных раком молочной железы; Перспективы развития фундаментальных наук; Т. 4 : Биология и фундаментальная медицина
| Parent link: | Перспективы развития фундаментальных наук=Prospects of Fundamental Sciences Development: сборник научных трудов XIV Международной конференции студентов, аспирантов и молодых ученых, г. Томск, 25-28 апреля 2017 г./ Национальный исследовательский Томский политехнический университет (ТПУ) ; под ред. И. А. Курзиной, Г. А. Вороновой.— , 2017 Т. 4 : Биология и фундаментальная медицина.— 2017.— [С. 112-114] |
|---|---|
| Autore principale: | |
| Altri autori: | , , , |
| Riassunto: | Заглавие с экрана In the present study, we performed the analysis of chitinase-like protein expression in specimens from patients with breast cancer. It was found that a higher risk of lymphogenous and hematogenous metastasis in patients with breast cancer was associated with a low level of YKL39 gene expression. We supposed that different variants of parenchymal-stromal-inflammatory relationship in tissue can determine the nature of lymphogenous and hematogenous metastasis, as well as the tumor response to chemotherapy. These processes are realized through the functional interrelation of cells of the inflammatory infiltrate and other components of tumor microenvironment with cells of the tumor itself. |
| Lingua: | russo |
| Pubblicazione: |
2017
|
| Soggetti: | |
| Accesso online: | http://earchive.tpu.ru/handle/11683/44869 |
| Natura: | Elettronico Capitolo di libro |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=625053 |
| Riassunto: | Заглавие с экрана In the present study, we performed the analysis of chitinase-like protein expression in specimens from patients with breast cancer. It was found that a higher risk of lymphogenous and hematogenous metastasis in patients with breast cancer was associated with a low level of YKL39 gene expression. We supposed that different variants of parenchymal-stromal-inflammatory relationship in tissue can determine the nature of lymphogenous and hematogenous metastasis, as well as the tumor response to chemotherapy. These processes are realized through the functional interrelation of cells of the inflammatory infiltrate and other components of tumor microenvironment with cells of the tumor itself. |
|---|