Цитогенетические последствия клещевых инфекций у рабочих нефтяных промыслов Сибири
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| Parent link: | Перспективы развития фундаментальных наук=Prospects of Fundamental Sciences Development: сборник научных трудов XIV Международной конференции студентов, аспирантов и молодых ученых, г. Томск, 25-28 апреля 2017 г./ Национальный исследовательский Томский политехнический университет (ТПУ) ; под ред. И. А. Курзиной, Г. А. Вороновой.— , 2017 Т. 4 : Биология и фундаментальная медицина.— 2017.— [С. 64-66] |
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| Outros autores: | , |
| Summary: | Заглавие с экрана This work consisted in monitoring of the cytogenetic effects in groups of oilfield workers infected with tick-borne infections: a group of patients with the coinfection of tick-borne encephalitis (TBE) and tick-borne ixodine borreliosis (TBB) in comparison with two groups of patients with mono-infection of one of these diseases. A total of 46 patients were examined including 12 ones with coinfection, 10 ones with TBB, and 24 individuals with TBE. Their peripheral blood samples for the chromosomal assay were obtained from the patients soon after being admitted to the hospital. In addition, the blood samples were repeatedly obtained from the same patients in 30, 60 and 180 days after being discharged from the hospital. The blood samples of healthy donors were used as the controls. It was found that in 2 day after being admitted to the hospital the frequency of cytogenetically damaged cells was significantly higher both in the coinfected (CI) and mono-infected patients than in the controls (p < 0.01). There were significant increases in the frequencies of both aneuploid and polyploid cells as well as in the lymphocytes with structural chromosomal aberrations, predominantly chromatid breaks. Most of the aneuploid cells belonged to the hypoploid type. The highest frequency of the aberrations was found in chromosome 2. In case of the full recovery (without chronicity), both the CI and TBE groups showed that the frequency of the cytogenetically damaged cells become statistically indistinguishable from the controls only in 6 months after the clinical recovery. In the patients with TBB, it occurs in a month after the clinical recovery. |
| Idioma: | ruso |
| Publicado: |
2017
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| Subjects: | |
| Acceso en liña: | http://earchive.tpu.ru/handle/11683/44853 |
| Formato: | Electrónico Capítulo de libro |
| KOHA link: | https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=624997 |
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