Optimization studies on extraction of phytocomponents from betel leaves; Resource-Efficient Technologies; Vol. 3, iss. 4

Bibliographic Details
Parent link:Resource-Efficient Technologies: electronic scientific journal/ National Research Tomsk Polytechnic University (TPU).— , 2015-.— 2405-6537
Vol. 3, iss. 4.— 2017.— [P. 385-393]
Other Authors: Muruganandam L, Anantha Krishna, Jashwanth Reddy, Nirmala G. S.
Summary:Title screen
The present study aims at finding out the optimum parameters for the extraction of components from Betel leaves possessing medicinal applications using ethanol solvent by Soxhlet apparatus. The optimum conditions for the extract were calculated based on the extract yield by varying four parameters: material quantity (A: 2-4 g), solvent quantity (B: 250-300 ml), mantle temperature (C: 65-75 °C) and extraction time (D: 1-3 hours) and optimized using a four factor three level Box-Behnken response surface design (BBD) coupled with desirability function methodology. Results showed that temperature and extraction time had significant effect on yield of extract. Optimum conditions for highest yield of extract (10.94%) are as follows: material quantity (2 g), solvent quantity (281.4 ml), temperature (72 °C) and time (3 hours). The extract at the maximum yield condition was analyzed for phytocomponents by FTIR and GC-MS. The results indicated the presence of Hydroxy chavicol (69.46%), 4-Chromanol (24%) and Eugenol (4.86%), which possess wide application including as antioxidant, anti-inflammatory, anti-platelet and antithrombotic, antibacterial and antifungal agents.
Language:English
Published: 2017
Subjects:
Online Access:http://earchive.tpu.ru/handle/11683/50319
Format: Electronic Book Chapter
KOHA link:https://koha.lib.tpu.ru/cgi-bin/koha/opac-detail.pl?biblionumber=575703

MARC

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330 |a The present study aims at finding out the optimum parameters for the extraction of components from Betel leaves possessing medicinal applications using ethanol solvent by Soxhlet apparatus. The optimum conditions for the extract were calculated based on the extract yield by varying four parameters: material quantity (A: 2-4 g), solvent quantity (B: 250-300 ml), mantle temperature (C: 65-75 °C) and extraction time (D: 1-3 hours) and optimized using a four factor three level Box-Behnken response surface design (BBD) coupled with desirability function methodology. Results showed that temperature and extraction time had significant effect on yield of extract. Optimum conditions for highest yield of extract (10.94%) are as follows: material quantity (2 g), solvent quantity (281.4 ml), temperature (72 °C) and time (3 hours). The extract at the maximum yield condition was analyzed for phytocomponents by FTIR and GC-MS. The results indicated the presence of Hydroxy chavicol (69.46%), 4-Chromanol (24%) and Eugenol (4.86%), which possess wide application including as antioxidant, anti-inflammatory, anti-platelet and antithrombotic, antibacterial and antifungal agents. 
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